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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK4
All Species:
13.64
Human Site:
S351
Identified Species:
27.27
UniProt:
Q96L34
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96L34
NP_113605.2
752
82520
S351
T
R
E
E
I
K
E
S
L
T
S
Q
K
Y
N
Chimpanzee
Pan troglodytes
XP_512745
736
81102
S336
T
R
E
E
I
K
E
S
L
T
S
Q
K
Y
N
Rhesus Macaque
Macaca mulatta
XP_001105523
666
73735
S310
G
P
E
V
D
I
W
S
L
G
V
I
L
Y
T
Dog
Lupus familis
XP_541564
690
76525
E333
V
G
M
G
Y
T
R
E
E
I
K
E
A
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIP4
752
82625
A351
T
R
E
E
I
K
E
A
L
T
N
Q
K
Y
N
Rat
Rattus norvegicus
Q8VHF0
797
88733
S348
S
Q
E
E
I
Q
E
S
L
S
K
M
K
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508081
736
82480
S340
S
Q
E
E
I
Q
E
S
L
S
K
M
K
Y
D
Chicken
Gallus gallus
Q9IA88
798
88848
R318
M
Q
T
L
G
I
D
R
Q
R
T
V
E
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
F351
M
A
M
A
E
M
G
F
D
R
E
R
T
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
I462
L
G
F
N
K
A
A
I
L
E
S
V
E
K
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
N156
L
L
L
D
S
R
C
N
I
K
I
A
D
F
G
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
P277
T
L
P
K
F
L
S
P
G
A
A
G
L
I
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
75.8
88.4
N.A.
97.6
60.4
N.A.
64.4
32.4
N.A.
29.3
N.A.
N.A.
N.A.
34.8
N.A.
Protein Similarity:
100
94.4
77.9
89.3
N.A.
98.9
73.5
N.A.
77.3
50
N.A.
41.2
N.A.
N.A.
N.A.
46.9
N.A.
P-Site Identity:
100
100
26.6
0
N.A.
86.6
53.3
N.A.
53.3
0
N.A.
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
26.6
6.6
N.A.
100
86.6
N.A.
86.6
26.6
N.A.
6.6
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.5
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.8
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
9
9
9
0
9
9
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
9
0
9
0
9
0
0
0
9
0
17
% D
% Glu:
0
0
50
42
9
0
42
9
9
9
9
9
17
0
9
% E
% Phe:
0
0
9
0
9
0
0
9
0
0
0
0
0
9
0
% F
% Gly:
9
17
0
9
9
0
9
0
9
9
0
9
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
42
17
0
9
9
9
9
9
0
9
0
% I
% Lys:
0
0
0
9
9
25
0
0
0
9
25
0
42
9
9
% K
% Leu:
17
17
9
9
0
9
0
0
59
0
0
0
17
17
9
% L
% Met:
17
0
17
0
0
9
0
0
0
0
0
17
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
9
0
0
9
0
0
0
25
% N
% Pro:
0
9
9
0
0
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
25
0
0
0
17
0
0
9
0
0
25
0
0
9
% Q
% Arg:
0
25
0
0
0
9
9
9
0
17
0
9
0
0
0
% R
% Ser:
17
0
0
0
9
0
9
42
0
17
25
0
0
9
0
% S
% Thr:
34
0
9
0
0
9
0
0
0
25
9
0
9
0
17
% T
% Val:
9
0
0
9
0
0
0
0
0
0
9
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _